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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 3
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Research Article

Effects of rice bran fibre and cholestyramine on the faecal excretion of Kanechlor 600 (PCB) in rats

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Pages 351-357 | Received 26 Mar 1990, Accepted 20 Sep 1990, Published online: 22 Sep 2008
 

Abstract

1. As rice bran fibre binds Kanechlor 600 (PCB), the present study was conducted to determine whether the fibre stimulates rat faecal excretion of PCB in vivo.

3. In rats fed these diets, PCB concentration of the small intestine was significantly decreased to 25-50% of that of controls. PCB of spleen in rats fed diets of 10% fibre, 10% fibre plus 5% lignin and 10% fibre plus 5% cholestyramine also decreased to 50% of that of controls. However, PCB of other tissues were not affected.

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