Severe adenomyosis and CA125

Abstract

A total of 50 women having uterine enlargement of > 12 weeks’ size due to severe adenomyosis with raised CA125, were carefully studied and compared with other cases. The greater the enlargement of the uterus over 240 cm³ volume or 12 weeks’ uterine size due to severe adenomyosis, the greater was the rise of CA125 levels and these were disturbingly high in some cases. However, similarly enlarged uteri due to fibroids did not show a rise in CA125 levels above normal. Raised CA125 thus need not instil anxiety, when the clinical findings are benign.

Keywords::

• Adenomyosis
• CA125
• large uterus
• severe adenomyosis
• uterine fibroids

Acknowledgement

The authors sincerely thank Dr V. Karani for compiling this manuscript.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.