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Summary
Summary
The ultrastructure of the placenta at 8 weeks' gestational age from intra-uterine (normal and an anembryonic pregnancy), a spontaneous tubal ectopic pregnancy and an ‘artificial' tubal ectopic pregnancy occurring after intraperitoneal insemination with husband's washed capacitated spermatozoa, was compared. Poorly developed chorionic villus epithelium and reduced stromal differentiation in an anembryonic intra-uterine pregnancy shows the importance of the embryo for placental development. In a spontaneous ectopic pregnancy chorionic villous epithelium and cellular differentiation with vasculogenesis in the stroma did not show the same developmental capacity as normal intrauterine pregnancies. Electron microscope observations showed close similarity between normal intra-uterine and an artificial tubal pregnancy. Husband's washed capacitated spermatozoa may affect placenta development beneficially.