Local male hormonal therapy in male infertility: A preliminary report

M. S. Fahim Department of Obstetrics and Gynecology, University of Missouri Medical School, Columbia, Missouri; Missouri and the Male Sterility Clinic and Andrology Section, Faculty of Medicine, Cairo University, Cairo, Egypt

S. M. Girgis Department of Obstetrics and Gynecology, University of Missouri Medical School, Columbia, Missouri; Missouri and the Male Sterility Clinic and Andrology Section, Faculty of Medicine, Cairo University, Cairo, Egypt

A. A. Ibrahim Department of Obstetrics and Gynecology, University of Missouri Medical School, Columbia, Missouri; Missouri and the Male Sterility Clinic and Andrology Section, Faculty of Medicine, Cairo University, Cairo, Egypt

A. Karaksy Department of Obstetrics and Gynecology, University of Missouri Medical School, Columbia, Missouri; Missouri and the Male Sterility Clinic and Andrology Section, Faculty of Medicine, Cairo University, Cairo, Egypt

Abstract

The therapeutic effect of local infiltration of the testis by testosterone crystalline suspension was studied in 18 cases of severe oligozoospermia. Evaluation was done by semen analysis follow-up, and results were correlated with preoperative testicular biopsies. About 40% of the cases showed improvement of sperm count and/or motility. Testicular biopsies of responding cases showed mild inhibitory changes, such as sloughing or partial spermatogenic arrest at late stages, while cases with tubular hyalinization or spermatogenic arrest at the stage of spermatogonia showed no response. The method proved to be simple, safe, and promising.

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Local male hormonal therapy in male infertility: A preliminary report

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Local male hormonal therapy in male infertility: A preliminary report

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