Deoxyribonuclease Activity in Human Sperm

R. Singer Male Fertility Laboratory, Beilinson Medical Center, and the Connective Tissue Research Unit Hasharon Medical Center, Petah Tikva, Israel

H. Levinsky Male Fertility Laboratory, Beilinson Medical Center, and the Connective Tissue Research Unit Hasharon Medical Center, Petah Tikva, Israel

M. Sagiv Male Fertility Laboratory, Beilinson Medical Center, and the Connective Tissue Research Unit Hasharon Medical Center, Petah Tikva, Israel

M. Barnet Male Fertility Laboratory, Beilinson Medical Center, and the Connective Tissue Research Unit Hasharon Medical Center, Petah Tikva, Israel

C. Servadio Male Fertility Laboratory, Beilinson Medical Center, and the Connective Tissue Research Unit Hasharon Medical Center, Petah Tikva, Israel

D. Allalouf Male Fertility Laboratory, Beilinson Medical Center, and the Connective Tissue Research Unit Hasharon Medical Center, Petah Tikva, Israel

Abstract

A previous failure to detect DNase activity in human sperm sonicates was ascribed to an inadequate amount of sperm used. In the present work aliquots contained more sperm (1.5-2.5/10⁶), permitting the detection of enzyme activity. The latter was significantly higher in spermatozoa of oligozoospermic origin compared with activity in normospermic specimens.

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Deoxyribonuclease Activity in Human Sperm

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Deoxyribonuclease Activity in Human Sperm

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