Review of Biologic Therapies

Abstract

The emergence of biologic therapy as treatment for autoimmune and inflammatory diseases is rapidly changing the face of medicine. From fusion proteins to monoclonal antibodies, biologic therapies encompass a variety of agents that target distinct pathways involved in autoimmunity and inflammation. In this review, a survey of available and emerging biologic therapies detailing their current indications, mechanism of action, dosing, side effects, and recommended drug monitoring will be summarized so as to aid clinicians in making treatment decisions regarding their usage.

KEYWORDS::

• Etanercept
• adalimumab
• infliximab
• abatacept
• anakinra
• rituximab
• golimumab
• certolizumab
• tocilizumab

ACKNOWLEDGEMENTS

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.