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Abstract
We present a case of orbital mucosa-associated lymphoid tissue (MALT) lymphoma accompanied by a serous retinal detachment (SRD). A 44-year-old man who developed uveitis accompanied by a SRD in the right eye was referred to the Chiba National Hospital. B-mode ultrasonography and magnetic resonance imaging (MRI) showed a thickened choroidal membrane and a retrobulbar mass. Although topical steroid treatments improved the inflammation, the SRD did not improve. He was then referred to the Chiba University Hospital. Two months later, the retrobulbar mass had increased, and a partial resection biopsy combined with flow cytometry was performed. The final diagnosis was MALT lymphoma. After R-CHOP (rituximab–cyclophosphamide, doxorubicin, vincristine, and prednisolone) chemotherapy, signs of the tumour could not be detected and the SRD was reduced. We conclude that the SRD was most likely due to the infiltration of lymphoma cells and also to choroidal circulatory disturbances. Retrobulbar malignant lymphomas associated with a SRD are very rare and difficult to diagnosis without biopsy, but because early diagnosis is helpful in deciding the appropriate therapy, we recommend partial biopsy.
Acknowledgements
The authors thank Professor Duco Hamasaki for editing the manuscript.
Declaration of interest: The case study is supported by the grant from The Eye Research Foundation of the Aged and a Grant-in Aid from the Ministry of Education, Science, Sports and Culture of the Japanese Government.
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.
Note: Figures 1, 3, and 4 of this article are available in colour online at http://informahealthcare.com/oph.