Opsoclonus — a cerebellar disorder?

Abstract

The fifteenth autopsied case (the third due to presumed viral encephalitis) of opsoclonus is reported. While opsoclonus generally occurs only in a few specific clinical settings, the anatomical localization and degree of the pathological abnormalities are very variable. This may be because the responsible lesion is biochemically specific but anatomically diffuse and thus, to a variable extent, eludes standard neuropathological techniques.