Bilateral pupillary cholinergic supersensitivity in a case of sarcoidosis

Abstract

The authors describe a case with sarcoidosis and bilateral internal ophthalmoplegia and no extraocular muscle dysfunction. Pupillary constriction to 0.1% pilocarpine was found with normal corneas, no uveitis, and normal corneal sensation. This case most likely had sarcoid involvement of the ciliary ganglia bilaterally with denervation supersensitivity of the pupillary sphincters.

Key Words:

• cholinergic supersensitivity
• sarcoidosis
• internal ophthalmoplegia