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Abstract
A 48-year-old female presented with bilateral paralysis of supranuclear hori zontal conjugated gaze and impairment of various pontine, cerebellar and cervical spinal cord functions.
The clinical signs and laboratory work-up indicated myeloencephalitis, probably of viral etiology. Paralysis of supranuclear horizontal conjugated gaze was produced experimentally by damaging the paramedial pontine reticularformation(PPRF). In the human, this a bnor-mality is extremely rare and, to the best of our knowledge, has not been reported previously in reversible encephalitis.