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Abstract
Magnetic resonance imaging (MRI) demonstrated several hyperintense white matter lesions in the brain of 15/20 patients with acute optic neuritis. The patients were categorized into three groups based on history and physical. Group 1 (11/20 patients) consisted of patients with isolated optic neuritis, six of which had abnormal MRI scans. Group 2 (8/20 patients) consisted of patients with probable multiple sclerosis (MS). Group 3 (one patient) consisted of patients with definite MS. All of the patients in Groups 2 and 3 had abnormal MRI scans. There was no difference between the extent or location of MRI demonstrated lesions between these three groups of patients with optic neuritis. Patients with isolated optic neuritis were just as likely to have extensive areas of involvement on MRI, as patients with probable or definite multiple sclerosis.