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Neuro-Ophthalmology Volume 7, 1987 - Issue 5
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Original Article

See-saw nystagmus and brainstem infarction MRI finclings

Daniel S. Kanter Departments of Neurology Cleveland Veterans Administration Medical Center and Case Western Reserve, University School of Medicine, Cleveland, OH, 44106, USA
,
R. L. Ruff Departments of Neurology Cleveland Veterans Administration Medical Center and Case Western Reserve, University School of Medicine, Cleveland, OH, 44106, USA
,
R. John Leigh Departments of Neurology Cleveland Veterans Administration Medical Center and Case Western Reserve, University School of Medicine, Cleveland, OH, 44106, USA
&
Michael Modic Departments of Radiology University Hospitals of Cleveland and Case Western Reserve, University School of Medicine, Cleveland, OH, 44106, USA
Pages 279-283 | Accepted 19 Jun 1987, Published online: 08 Jul 2009
 
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Abstract

A patient with see-saw nystagmus had a lesion localized by Magnetic Resonance Imaging (MRI) to the paramedian ventral midbrain with involvement of the right interstitial nucleus of Cajal. This is the first MRI study of see-saw nystagmus associated with a presumed brainstem vascular event. Our finclings support animal and human studies suggesting that dysfunction of the interstitial nucleus of Cajal or its connections is central in this disorder.

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