4
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Pupillary symptoms in three patients with pandysautonomia

, &
Pages 87-93 | Accepted 14 Mar 1988, Published online: 08 Jul 2009
 

Abstract

Three cases of pandysautonomia are discussed, with particular emphasis on the pupillary disturbances involved. Pupillary reactions were examined with infrared pupillography. In Case 1, early symptoms included internal ophthalmoplegia of both eyes. Five months later, recovery was complete in the left eye, but incomplete in the right. Cases 2 and 3 showed bilateral or unilateral tonic pupils. Dilatation upon instillation of a low concentration of epinephrine revealed hypersensitive pupil responses in all three cases. The instillation of a low concentration of methacholine resulted in miosis in all cases. These responses suggest that the main lesion was located in the postganglionic fibers of both the sympathetic and parasympathetic neurons of the pupils. They also suggest either that there was recovery from the initial internal ophthalmoplegia or that it changed to tonic pupils at a later stage.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.