Aseptic meningitis with retinal ischemia due to trimethoprim-sulfamethoxazole

Abstract

The authors present the first case report of an aseptic meningitis associated with a uniquely documented retinal ischemia due to trimethoprim-sulfamethoxazole.

A 20-year-old woman suffered an aseptic meningitis with retinal ischemia OU, due to ingestion of Bactrim. This case highlights the potential for neuro-ophthalmic side effects of the preparation. Review of the literature and their experience suggest that prompt recognition of the syndrome and withdrawal of the drug is necessary to prevent serious neurologic complications and visual loss.

Key Words:

• aseptic meningitis
• visual loss
• trimethoprim
• sulfonamide
• ischemia
• retinal vasculitis
• drug-induced hypersensitivity