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Original Article

Congenital bilateral horizontal gaze palsy in two adult patients

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Pages 115-119 | Accepted 16 Sep 1991, Published online: 08 Jul 2009
 

Abstract

Two cases of bilateral horizontal gaze palsy were for the first time diagnosed in adulthood. The past history pointed to a congenital condition. MRI and BAEP were normal in either patient. EOG revealed disturbance of horizontal saccades as well as smooth pursuit in both. There was no nystagmus to vestibular stimuli in one patient. In the other, vertical eye movements were abnormal. The pathophysiology is discussed with respect to the literature, but remains ill-defined. The findings cannot be explained by bilateral lesion of the PPRF, but may be a variant of bilateral Stilling-Türk-Duane syndrome.

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