A pilot study of gabapentin as treatment for acquired nystagmus

L. Averbuch-Heller Department of Neurology, Department of Veterans Affairs Medical Center, University Hospitals, Case Western Reserve University, Cleveland, OH, USA

J. S. Stahl Department of Neurology, Department of Veterans Affairs Medical Center, University Hospitals, Case Western Reserve University, Cleveland, OH, USA

K. G. Rottach Department of Neurology, Department of Veterans Affairs Medical Center, University Hospitals, Case Western Reserve University, Cleveland, OH, USA

L. Averbuch-Heller Department of Neurology, Department of Veterans Affairs Medical Center, University Hospitals, Case Western Reserve University, Cleveland, OH, USA

R. D. Von Maydell Department of Neurology, Department of Veterans Affairs Medical Center, University Hospitals, Case Western Reserve University, Cleveland, OH, USA

S. D. Collins Department of Neurology, Department of Veterans Affairs Medical Center, University Hospitals, Case Western Reserve University, Cleveland, OH, USA

R. J. Leigh Department of Neurology, Department of Veterans Affairs Medical Center, University Hospitals, Case Western Reserve University, Cleveland, OH, USA

show all

Abstract

The effects of the anticonvulsant gabapentin were measured on vision and eye movements in three patients with acquired pendular nystagmus. In two patients, the nystagmus was associated with multiple sclerosis and, in the other, i t followed brainstem stroke. A single oral 600 mg dose of gabapentin produced improvement of vision due to changes i n ocular oscillations in all three patients. The effect was sustained after five weeks of treatment in two patients who elected to continue taking gabapentin 900-1500 mg/day. The results of this pilot study suggest that a controlled trial of gabapentin should be conducted to evaluate its role i n the treatment of acquired forms of nystagmus.

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

A pilot study of gabapentin as treatment for acquired nystagmus

Information for

Open access

Opportunities

Help and information

A pilot study of gabapentin as treatment for acquired nystagmus

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature