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Original Article

Acquired peripapillary myelination associated with chronic papilledema

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Pages 31-34 | Accepted 13 May 1996, Published online: 08 Jul 2009
 

Abstract

A patient with papilledema due to idiopathic intracranial hypertension developed bilateral progressive peripapillary myelination. This acquired myelination suggests a breakdown of the normal barrier to oligodendrocyte migration into the retina. However, ultrastructural studies of developmental and acquired myelination in animals have consistently found that the myelin is formed by peripheral nervous system myelin forming cells (Schwann cells) rather than central nervous system oligodendrocytes.

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