Side-to-side differences in visual event-related potentials but not VEP in patients with multiple sclerosis: A report of three cases

Abstract

Three patients with definite multiple sclerosis (MS) and acute loss of visual acuity on one side but without side-to-side differences in visual evoked potential (VEP) latencies revealed prolongation of visual event-related potentials (ERP) on the impaired side. These patients represent 5.1 % of a cohort with clinical optic mononeuritis and 21.4% of a cohort with clinical optic mononeuritis but no side-to-side differences in VEP. The data suggest, that in some cases, side different measurement of ERP (rather than VEP) is an appropriate method to prove the sensory or cognitive impairment in patients with MS and clinical optic mononeuritis.

Key Words:

• Multiple sclerosis
• visual evoked potentials
• visual event-related potentials