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The International Journal on Orbital Disorders, Oculoplastic and Lacrimal Surgery
Volume 35, 2016 - Issue 1
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Original Articles

A case of non-lacrimal immunoglobulin G4 (IgG4)-related orbital disease with mastitis

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Pages 16-19 | Received 10 Jul 2014, Accepted 21 Sep 2015, Published online: 23 Dec 2015
 

ABSTRACT

IgG4-related orbital disease is a recognised cause for orbital inflammation. As its awareness increases and diagnostic accuracy improves there will be an increased number of cases being identified. This unique case demonstrates for the first time, with histological evidence, a case of a non-lacrimal IgG4-related orbital disease with concurrent IgG4-related mastitis. We describe a 47 year old who presented with a supraorbital swelling and mass. This was initially successfully treated with oral steroids and was later excised on recurrence. Immunohistochemical and blood serum analysis confirmed IgG4-related orbital disease. On systemic enquiry she was found to have a mass of the breast, which was shown to be IgG4-related mastitis. She is currently asymptomatic with no sign of recurrence and is under long-term surveillance. This case highlights the importance of systemic work up in patients presenting with orbital foci of IgG4 disease.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

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