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Research Article

Examination of parameters determining particle size distribution: acetylsalicylic acid microcapsules

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Pages 21-25 | Received 22 Oct 1986, Accepted 29 Jan 1987, Published online: 27 Sep 2008
 

Abstract

A method of preparation of acetylsalicylic acid microcapsules has been elaborated. The active ingredient was made suitable for microencapsulation by recrystallization before phase separation coating. Experiments were performed on the basis of factorial design, and parameters which influence the particle size and particle size distribution of microcapsules were characterized quantitatively.

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