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Journal of Microencapsulation
Micro and Nano Carriers
Volume 9, 1992 - Issue 1
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Research Article

A new approach to encapsulating non-steroidal anti-inflammatory drugs. V. Biopharmaceutical study of microcapsules of azapropazone coated with pectin and rutin

M. M. Meshali Faculty of Pharmacy, Mansoura University, Island, USA
,
E. Z. El-Dien Faculty of Pharmacy, Mansoura University, Island, USA
,
S. A. Omar Faculty of Pharmacy, Mansoura University, Island, USA
&
L. A. Luzzi College of Pharmacy, University of Rhode, Island, USA
Pages 67-72 | Received 04 Feb 1991, Accepted 29 Apr 1991, Published online: 27 Sep 2008
 
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Abstract

Azapropazone was encapsulated with pectin-rutin mixture using the fluidized bed technique. The encapsulated particles showed higher dissolution rate and bioavailability but lower ulcerogenic activity as compared with the drug alone.

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