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Research Article

Effect of polybutadiene on the encapsulation efficiency of ethyl cellulose microcapsules of sulphadiazine

Pages 437-447 | Received 12 May 1992, Accepted 01 Jun 1992, Published online: 27 Sep 2008
 

Abstract

The coacervation-inducing effect of polybutadiene (PBD), a liquid telomer of butadiene, in microencapsulation of sulphadiazine was investigated, using phase separation coacervation of ethyl cellulose, by solvent alteration, in heavy mineral oil medium. The effects of protective colloids and core-wall ratio on encapsulation efficiency were studied. Efficacy of PBD was studied compared to polyisobutylene (PIB). Experimental results revealed that PBD ensured better encapsulation efficiency compared to PIB.

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