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Research Article

Influence of emulsifying agents on the properties of cellulose acetate butyrate and ethylcellulose microcapsules

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Pages 633-639 | Received 08 Jun 1993, Accepted 17 Jun 1993, Published online: 27 Sep 2008
 

Abstract

Microcapsules of ibuprofen were prepared according to the solvent evaporation method, using two coating polymers, cellulose acetate butyrate and ethylcellulose. The influence of two emulsifying agents, polysorbat 80 and polyvinyl alcohol, on the properties of the microcapsules was investigated. The results show that type and concentration of emulsifying agent influences size distribution, drug loading and amount of free drug on the surface of the microcapsules.

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