Comparison of microwave ablation and multipolar radiofrequency ablation, both using a pair of internally cooled interstitial applicators: Results in ex vivo porcine livers

Abstract

Purpose: To compare the effectiveness of microwave ablation (MWA) and multipolar radiofrequency ablation (RFA) in ex vivo porcine livers, in both cases using a pair of internally cooled interstitial applicators.

Materials and methods: MWA was performed on ex vivo porcine livers (n = 60) using a pair of simultaneously powered, internally cooled shaft interstitial antennae. Four power settings were used: 50 W, 60 W, 70 W and 80 W (n = 15 per setting). Multipolar RFA was also performed on ex vivo porcine livers (n = 30), also using a pair of simultaneously powered, internally cooled shaft interstitial bipolar applicators. This was performed for two applicator types T30 (3 cm length) and T40 (4 cm length) at a manufacturer prescribed power of 60 W and 80 W, respectively (n = 15 per applicator). Spacing between the two probes was 2 cm in all cases. Each power setting was applied for 15 ablations for 10 min each. The long-axis diameter (Dl), short-axis diameter (Ds) and the ratio Ds/Dl for each ablation were measured. Temperature data were recorded at 10 positions. Temperature curves were recorded at 3 locations, as well as the time required for the temperature to rise to 50°C.

Results: Dl and Ds for all the power settings of MWA were significantly larger than that of both kinds of multipolar RFA (P < 0.05). The rates of temperature to rise to 50°C in all the MW ablations power settings were significantly faster than those in both multipolar RF ablations.

Conclusion: MWA by the simultaneous application of double antennae may be more advantageous for treating larger liver tumour than multipolar RFA.

• Animals
• experimental study
• microwave
• multipolar radiofrequency
• ablation