Microwave applicator for transurethral hyperthermia of benign prostatic hyperplasia

M. A. Astrahan Department of Radiation Oncology, University of Southern California School of Medicine, Kenneth Norris Cancer Hospital, 1441 Eastlake Avenue, Los Angeles, California, 90033, USA

M. D. Sapozink Department of Radiation Oncology, University of Southern California School of Medicine, Kenneth Norris Cancer Hospital, 1441 Eastlake Avenue, Los Angeles, California, 90033, USA

D. Cohen Department of Radiation Oncology, University of Southern California School of Medicine, Kenneth Norris Cancer Hospital, 1441 Eastlake Avenue, Los Angeles, California, 90033, USA

G. Luxton Department of Radiation Oncology, University of Southern California School of Medicine, Kenneth Norris Cancer Hospital, 1441 Eastlake Avenue, Los Angeles, California, 90033, USA

T. D. Kampp Department of Radiation Oncology, University of Southern California School of Medicine, Kenneth Norris Cancer Hospital, 1441 Eastlake Avenue, Los Angeles, California, 90033, USA

S. Boyd Department of Urology, University of Southern California School of Medicine, Kenneth Norris Cancer Hospital, 1441 Eastlake Avenue, Los Angeles, California, 90033, USA

Z. Petrovich Department of Radiation Oncology, University of Southern California School of Medicine, Kenneth Norris Cancer Hospital, 1441 Eastlake Avenue, Los Angeles, California, 90033, USA

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Abstract

An applicator for heating the prostate gland using a transurethral approach is described. This technique uses three microwave antennas and a thermometry sensor attached to the outer surface of a balloon (Foley) type urological catheter. Each microwave antenna also includes a built-in thermistor to control temperature and balance power. The balloon catheter assures rapid and reproducible localization of the antennas in the prostatic urethra. The two-dimensional SAR and steady-state temperature distributions surrounding the applicator in tissue equivalent phantom are reported. Longitudinal temperature distributions measured in situ at the applicator-urethral interface and the longitudinal and radial temperature distributions measured in normal canine prostate are presented and discussed. The technique appears to be capable of elevating temperature to greater than 42°C in a cylindrically symmetrical volume up to 5 cm length and 0.5 cm radial penetration surrounding the applicator.

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Microwave applicator for transurethral hyperthermia of benign prostatic hyperplasia

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Microwave applicator for transurethral hyperthermia of benign prostatic hyperplasia

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