Rapid development of glioblastoma at the site of atypical meningioma resection

Abstract

The authors describe symptomatic presentation of glioblastoma within six months of resection of an atypical meningioma, at the same frontal parafalcine cerebral location. The patient had neither prior nor adjuvant radiotherapy nor known genetic risk factors. Possible links between invasive meningioma and transformation of adjacent glial cells or precursors to malignant glioma are discussed.

Key words:

• Infection
• Glioblastoma multiforme
• meningioma
• trauma

Acknowledgments

The authors thank Dr. Pieter Pretorius and Dr. James Morris for advice regarding neuroimaging and neuropathology, respectively.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.