The use of danaparoid to manage coagulopathy in a neurosurgical patient with heparin-induced thrombocytopenia type II and intracerebral haemorrhage

Abstract

This study presents a case of bifrontal intracerebral haemorrhage in a patient with heparin-induced thrombocytopenia type II (HIT II). HIT II was induced by treatment with low-molecular-weight heparin for recurrent deep vein thrombosis caused by essential thrombocytosis and accompanied by hepatic thromboembolism. This patient was treated with platelet substitution and neurosurgical haematoma evacuation. Anticoagulation with 2500 units danaparoid per day was sufficient for therapy of thrombosis and no rebleeding occurred.

Key words:

• Heparin-induced thrombocytopenia
• essential thrombocytosis
• intracerebral haemorrhage
• ICH
• low molecular weight heparin
• case report

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.