An approach to deep brain stimulation for severe treatment-refractory Tourette syndrome: the UK perspective

Andrea E. CavannaCorrespondence[email protected]

Clare M. Eddy

Rosalind MitchellDepartment of Neurosurgery, University of Birmingham and UHB, Birmingham, UK

Hardev PallDepartment of Neurology, University of Birmingham and UHB, Birmingham, UK

Ian MitchellDepartment of Psychology, University of Birmingham, Birmingham, UK

Ludvic ZrinzoSobell Department of Motor Neuroscience and Movement Disorders, Unit of Functional Neurosurgery, UCL Institute of Neurology, London, UK

Tom FoltynieSobell Department of Motor Neuroscience and Movement Disorders, Unit of Functional Neurosurgery, UCL Institute of Neurology, London, UK

Marjan Jahanshahi

Patricia LimousinSobell Department of Motor Neuroscience and Movement Disorders, Unit of Functional Neurosurgery, UCL Institute of Neurology, London, UK

Marwan I. HarizSobell Department of Motor Neuroscience and Movement Disorders, Unit of Functional Neurosurgery, UCL Institute of Neurology, London, UK

Hugh RickardsDepartment of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham, UK

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Abstract

Deep brain stimulation (DBS) is an emerging therapeutic option for severe, treatment-resistant Tourette Syndrome (TS), with about 40 cases reported in the scientific literature over the last decade. Despite the production of clinical guidelines for this procedure from both European and USA centres, a number of unresolved issues still persist, mainly in relation to eligibility criteria and brain targets. The present article illustrates the UK perspective on DBS in TS and proposes consensus-based recommendations for double-blind controlled trials.

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Acknowledgements

The authors thank UK-Tourettes Action for continuing support.

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An approach to deep brain stimulation for severe treatment-refractory Tourette syndrome: the UK perspective

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An approach to deep brain stimulation for severe treatment-refractory Tourette syndrome: the UK perspective

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