195
Views
22
CrossRef citations to date
0
Altmetric
Original Article

Effect of Aging on Optical Quality and Intraocular Scattering Using the Double-Pass Instrument

, , , , &
Pages 884-888 | Received 11 Feb 2012, Accepted 16 Apr 2012, Published online: 15 May 2012
 

Abstract

Purpose: To assess the effect of aging on optical quality in a normal population.

Methods: We prospectively examined 100 normal eyes of 100 healthy volunteers (50 men, 50 women; ages, 20–69 years; mean age ± standard deviation, 44.6 ± 15.5 years). We quantitatively assessed the values of MTF cutoff frequency, Strehl ratio, and objective scattering index (OSI), using an Optical Quality Analysis System™ (Visiometrics, Terrassa, Spain). We took these measurements three times each, and the mean value obtained was used for statistical analysis. We investigated the relationships between subject age and these optical quality parameters.

Results: The mean MTF cutoff frequency, Strehl ratio, and OSI, were 27.76 ± 8.41, 0.17 ± 0.05, and 1.29 ± 0.76 cycles/degree, respectively. We found a significant negative correlation between subject age and MTF cutoff frequency (Pearson’s correlation coefficient r = −0.606, p < 0.001), and between age and Strehl ratio (r = −0.649, p < 0.001). We also found a significant positive correlation between subject age and OSI (r = 0.691, p < 0.001).

Conclusions: The MTF cutoff frequency and the Strehl ratio are significantly decreased, and the OSI is significantly increased, by aging, indicating that the optical quality of the eye is degraded in older subjects.

Declaration of interest: None of the authors have a personal financial interest concerning the topic discussed in the manuscript. The authors alone are responsible for the content and writing of the paper.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.