10
Views
25
CrossRef citations to date
0
Altmetric
Original Article

Tumor destruction by intermediate level hyperthermia

, , , , &
Pages 771-780 | Received 12 Feb 1990, Accepted 05 Jul 1990, Published online: 02 Jul 2009
 

Abstract

The tumorocidal effect of hyperthermia was studied in Greene's amelanotic hamster melanoma transplanted into the anterior chamber of rabbit eyes. To achieve optimal depth penetration, hyperthermia was induced with near infrared light of 820–870 nm, during 15 minutes, at a beam diameter of 2.5–6.0 mm resulting in an intermediate level hyperthermia of 45–60°C.

At 45°C no tumor destruction occurred, at 50°C the effect varied from no destruction to total thickness tumor destruction. At 55–60°C total tumor destruction with additional lens damage occurred. In comparison photocoagulation with white light revealed only necrosis up to half the tumor thickness.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.