Localisation of the gene encoding diacylglycerol kinase 3 (DAGK3) to human chromosome 3q27-28 and mouse chromosome 16

Jude Fitzgibbon Department of Molecular Genetics, Institute of Ophthalmology, University of London, London, UK

Dagan Wells Department of Molecular Genetics, Institute of Ophthalmology, University of London, London, UK; Department of Genetics and Biometry, University College London, London, UK

Alison Pilz Department of Molecular Genetics, Institute of Ophthalmology, University of London, London, UK; Department of Genetics and Biometry, University College London, London, UK

Joy Delhanty Department of Molecular Genetics, Institute of Ophthalmology, University of London, London, UK; Department of Genetics and Biometry, University College London, London, UK

Masahiro Kai Department of Molecular Genetics, Institute of Ophthalmology, University of London, London, UK; Department of Biochemistry, Sapporo Medical College, Sapporo, Japan

Hideo Kanoh Department of Molecular Genetics, Institute of Ophthalmology, University of London, London, UK; Department of Biochemistry, Sapporo Medical College, Sapporo, Japan

David Hunt Department of Molecular Genetics, Institute of Ophthalmology, University of London, London, UK

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Abstract

The gene encoding a 90 kDa diacylglycerol kinase protein, DAGK3, that is predominately expressed in the retina, was localised by fluorescence in situ hybridisation to human chromosome 3q27-28. This was subsequently confirmed by mapping of its mouse homologue to chromosome 16, a region syntenic to this part of human chromosome 3. No retinopathies have so far been assigned to this region.

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Localisation of the gene encoding diacylglycerol kinase 3 (DAGK3) to human chromosome 3q27-28 and mouse chromosome 16

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Localisation of the gene encoding diacylglycerol kinase 3 (DAGK3) to human chromosome 3q27-28 and mouse chromosome 16

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