17
Views
22
CrossRef citations to date
0
Altmetric
Original Article

Changes in Bronchial Reactivity in Asthmatic Children After Treatment with Beclomethasone Alone or in Association with Salbutamol

, , , , &
Pages 359-364 | Published online: 02 Jul 2009
 

Abstract

Airway inflammation is consistently present in patients with severe asthma. The combination of inhaled steroids and bronchodilators may be useful both for treating symptoms and improving the underlying inflammatory condition. We have compared the effect of beclomethasone dipropionate (BDP) combined with salbutamol (S), BDP alone, and placebo, on the severity of bronchial responsiveness in 30 children with allergic asthma during the period of specific allergen exposure.

In children treated with BDP alone, PC20-FEV, methacholine was 0.66 ± 0.54 at the beginning and 1.91 ±2.11 at the end of the study period (p>0.05). In children treated with BDP+S PC20, methacholine was 1.21 ± 1.43 at the beginning and 4.22 ± 3.88 at the end of the study (p<0.05). The group of children treated with placebo had a PC20-FEV methacholine of 0.79 ± 0.61 at the beginning of the study and 0.80 ± 0.46

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.