Serum Thymidine Kinase as a Prognostic Marker in Hodgkin's Disease

B. Eriksson THE DEPARTMENTS OF ONCOLOGY, MEDICINE AND PATHOLOGY, UNIVERSITY HOSPITAL, S-75185, UPPSALA; THE DEPARTMENT OF VIROLOGY, BIOMEDICAL CENTER, UPPSALA UNIVERSITY, S-75105, UPPSALA, SWEDEN

H. Hagberg THE DEPARTMENTS OF ONCOLOGY, MEDICINE AND PATHOLOGY, UNIVERSITY HOSPITAL, S-75185, UPPSALA; THE DEPARTMENT OF VIROLOGY, BIOMEDICAL CENTER, UPPSALA UNIVERSITY, S-75105, UPPSALA, SWEDEN

B. Glimelius THE DEPARTMENTS OF ONCOLOGY, MEDICINE AND PATHOLOGY, UNIVERSITY HOSPITAL, S-75185, UPPSALA; THE DEPARTMENT OF VIROLOGY, BIOMEDICAL CENTER, UPPSALA UNIVERSITY, S-75105, UPPSALA, SWEDEN

C. Sundström THE DEPARTMENTS OF ONCOLOGY, MEDICINE AND PATHOLOGY, UNIVERSITY HOSPITAL, S-75185, UPPSALA; THE DEPARTMENT OF VIROLOGY, BIOMEDICAL CENTER, UPPSALA UNIVERSITY, S-75105, UPPSALA, SWEDEN

S. Gronowitz THE DEPARTMENTS OF ONCOLOGY, MEDICINE AND PATHOLOGY, UNIVERSITY HOSPITAL, S-75185, UPPSALA; THE DEPARTMENT OF VIROLOGY, BIOMEDICAL CENTER, UPPSALA UNIVERSITY, S-75105, UPPSALA, SWEDEN

C. Källander THE DEPARTMENTS OF ONCOLOGY, MEDICINE AND PATHOLOGY, UNIVERSITY HOSPITAL, S-75185, UPPSALA; THE DEPARTMENT OF VIROLOGY, BIOMEDICAL CENTER, UPPSALA UNIVERSITY, S-75105, UPPSALA, SWEDEN

Abstract

In 72 of 81 consecutively diagnosed patients with Hodg-kin's disease pretreatment sera were available for analysis of serum thymidine kinase (S-TK) levels. In relation to clinical parameters, such as stage, histopathology and general symptoms, significant correlations were found with higher (S-TK) levels in advanced disease as well as in patients with B-symptoms. When the prognostic ability was examined, patients in stages IA and IIA could be divided according to S-TK levels into two different groups in relation to disease-free survival. This latter finding makes this serum test interesting as an additional tool in the clinical evaluation and in the therapeutic decision concerning patients with Hodgkin's disease.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Serum Thymidine Kinase as a Prognostic Marker in Hodgkin's Disease

Related Research Data

Information for

Open access

Opportunities

Help and information

Serum Thymidine Kinase as a Prognostic Marker in Hodgkin's Disease

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related Research Data

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature