Breast Cancer ^99mTc Sm3 Radioimmunoscintigraphy

Maria Granowska St. Bartholomew's Hospital and Medical College Imperial Cancer Research Fund, ICRF, Nuclear Medicine Group, London, UK

Lorenzo Biassoni St. Bartholomew's Hospital and Medical College Imperial Cancer Research Fund, ICRF, Nuclear Medicine Group, London, UK

Melvyn J. Carroll St. Bartholomew's Hospital and Medical College Imperial Cancer Research Fund, ICRF, Nuclear Medicine Group, London, UK

Robert Howell St. Bartholomew's Hospital and Medical College Imperial Cancer Research Fund, ICRF, Nuclear Medicine Group, London, UK

Steven J. Mather St. Bartholomew's Hospital and Medical College Imperial Cancer Research Fund, ICRF, Nuclear Medicine Group, London, UK

David Ellison St. Bartholomew's Hospital and Medical College Imperial Cancer Research Fund, ICRF, Nuclear Medicine Group, London, UK

Arthur Granowski St. Bartholomew's Hospital and Medical College Imperial Cancer Research Fund, ICRF, Nuclear Medicine Group, London, UK

Keith E. Britton St. Bartholomew's Hospital and Medical College Imperial Cancer Research Fund, ICRF, Nuclear Medicine Group, London, UK

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Abstract

^99mTc SM3 radioimmunoscintigraphy is combined with kinetic analysis and probability mapping using a change detection algorithm to investigate axillary node involvement before primary surgery in patients with breast cancer. Whereas planar imaging was unsuccessful, axillary node involvement was correctly determined in 11 out of 13 patients 6 out of 7 true negatives and 5 out of 6 true positives down to 0.35 grams. A prospective study is underway

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Breast Cancer ^99mTc Sm3 Radioimmunoscintigraphy

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Breast Cancer 99mTc Sm3 Radioimmunoscintigraphy

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Breast Cancer ^99mTc Sm3 Radioimmunoscintigraphy