Abstract
In an experimental series in dogs large mandibular and tibial defects were reconstructed by using a titanium splint to re-establish skeletal continuity and autologous grafts of spongious bone and marrow compensating for the bone removed. The results of this experimental investigation were used to design a method for repair of mandibular defects in man. With the aid of titanium splints and autologous bone and marrow grafts the anatomy of the mandible could be restituted and immediate function achieved. The results of application of these principles for repair of mandibular defects in 10 cases are reported.