Radiation-Sterilized Split Skin: A new type of Biological Wound Dressing: A Preliminary Report

B. Köurlof Department of Plastic Surgery (Head: B. NyléAn), Karolinska Sjukhuset, and the National Institute of Radiation Protection (Head: B. Lindell), Stockholm, Sweden

E. Simoni Department of Plastic Surgery (Head: B. NyléAn), Karolinska Sjukhuset, and the National Institute of Radiation Protection (Head: B. Lindell), Stockholm, Sweden

I. Bårryd Department of Plastic Surgery (Head: B. NyléAn), Karolinska Sjukhuset, and the National Institute of Radiation Protection (Head: B. Lindell), Stockholm, Sweden

L. O. Lamke Department of Plastic Surgery (Head: B. NyléAn), Karolinska Sjukhuset, and the National Institute of Radiation Protection (Head: B. Lindell), Stockholm, Sweden

G. Eriksson Department of Plastic Surgery (Head: B. NyléAn), Karolinska Sjukhuset, and the National Institute of Radiation Protection (Head: B. Lindell), Stockholm, Sweden

Abstract

Thin split skin grafts from human cadavers have been killed and sterilized by irradiation (4 ± 1 Mrad). This issue has successfully been used as a biological dressing on donor areas, second and third degree burns. It reduces the evaporation from the wound surfaces by 85%. Electron microscopic investigation shows that the horny layer of the dead tissue is well preserved in spite of the heavy irradiation, which explains the beneficial properties of this biological dressing.

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Radiation-Sterilized Split Skin: A new type of Biological Wound Dressing: A Preliminary Report

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Radiation-Sterilized Split Skin: A new type of Biological Wound Dressing: A Preliminary Report

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