Cardiac Output and Regional Blood Flow in Untreated and Triglycylvasopressin-Treated Burned Mice

Abstract

Cardiac output and regional blood flow to different organs were determined at one hour and at 24 hours after burn in untreated mice and in mice treated with triglycylvasopressin (TGLVP). A decrease in cardiac output was found in all animals at one hour after burn. At 24 hours cardiac output was decreased in the burned untreated group, while cardiac output of TGLVP-treated animals did not differ from that of unburned animals. Organ blood flow was decreased in all animals at one hour after burn. Such a decrease was seen in the untreated group also at 24 hours after burn, while organ blood flow in the TGLVP-treated group had returned to preburn values.