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Scandinavian Journal of Plastic and Reconstructive Surgery Volume 16, 1982 - Issue 3
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Original Article

Immunoreactive Alpha2-Macroglobulin in Rheumatoid Synovial Membrane

Lars Ekerot Department of Hand Surgery (Head: O. Eiken) and the Department of Experimental Research (Head: S. E. Bergentz), Allmänna sjukhuset, Malmö, Sweden
&
Kjell Ohlsson Department of Hand Surgery (Head: O. Eiken) and the Department of Experimental Research (Head: S. E. Bergentz), Allmänna sjukhuset, Malmö, Sweden
Pages 293-294 | Received 15 Dec 1981, Published online: 08 Jul 2009
 
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Abstract

$aL2-Macroglobulin was demonstrated immuno-histochemically in macrophage-like cells of rheumatoid arthritic synovial tissue. It is concluded that these intra-cellular deposits probably represent phagocytosed protease-$aL2-macroglobulin complexes. A contributing local production of $aL2-macroglobulin is, however, not excluded by the present findings.

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