Phenylalanine: Total Amino Acid Ratio in 45 Burn Patients

Abstract

In 45 burn patients serum amino acids together with liver enzymes and other serum parameters were determined. Phe levels, Phe:Tyr and Phe:TAA ratios were correlated with the clinical course of the patient's condition. Based on empirical data, an increase in the Phe: TAA ratio of over 3 % was found to be the best indicator of a critical period in the clinical course. An increase in the Phe: TAA ratio above 3 % accompanied the signs of sepsis. If the patient recovered, the ratio decreased. Ratios which kept constant or even increased –indicating a possible fatal clinical outcome—were found to be alarming. In our experience Phe levels or Phe:Tyr ratios did not have indicative functions.

Key Words:

• amino acids
• Phenylalanine
• burns