Abstract
In 24 adult RA patients with knee joint synovitis and bilateral hydrops, the worse joint clinically was treated with osmic acid and 50 mg of hydrocortisone acetate, while the better joint clinically was treated with 40 mg of methylprednisoione acetate (Depot Medrol®). After 6 months, hydrops was palpable in 8 joints treated with osmic acid and in 15 joints treated with corticosteroid only. Pain relief was more marked in joints treated with osmic acid.