Significance of C-Reactive Protein Elevation in the Pretreatment Stage of Systemic Lupus Erythematosus

Takatoshi Inoue First Department of Internal Medicine, Osaka City University Medical School, Asahimachi, Abenoku, Osaka, Japan

Yoshiharu Kanayama First Department of Internal Medicine, Osaka City University Medical School, Asahimachi, Abenoku, Osaka, Japan

Noriyuki Katoh First Department of Internal Medicine, Osaka City University Medical School, Asahimachi, Abenoku, Osaka, Japan

Akiko Ohe First Department of Internal Medicine, Osaka City University Medical School, Asahimachi, Abenoku, Osaka, Japan

Koji Amatsu First Department of Internal Medicine, Osaka City University Medical School, Asahimachi, Abenoku, Osaka, Japan

Mikio Okamura First Department of Internal Medicine, Osaka City University Medical School, Asahimachi, Abenoku, Osaka, Japan

Tetsuo Horiguchi First Department of Internal Medicine, Osaka City University Medical School, Asahimachi, Abenoku, Osaka, Japan

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Abstract

The significance of Oreactive protein (CRP) elevation in patients with systemic lupus erythematosus (SLE) in the pretreatment stage was assessed with reference to other laboratory data obtained simultaneously. Sixteen of 31 cases were CRP-positive, and the CRP-positive group contained significantly more cases with urinary cellular casts and with a high anti-DNA antibody titer, compared with the CRP-negative group. We suggest that CRP in patients with SLE, as measured at the time of the first consultation, reflects the severity of the disease. This includes those cases complicated by nephropathy.

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Significance of C-Reactive Protein Elevation in the Pretreatment Stage of Systemic Lupus Erythematosus

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