Xerostomia in Sjögren's Syndrome Treated with Sali-Synt®: A Double-blind Cross-over Trial

Abstract

In a double-blind cross-over trial, a new synthetic saliva Sali-Synt® was compared with placebo for the treatment of xerostomia in Sjögren's syndrome. Sali-Synt® may soothe the pain in the mouth and reduces sleep disturbances better than placebo, but no statistically significant differences were found. Seven patients of 12 preferred Sali-Synt® to placebo in helping xerostomia.