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Abstract
The syndrome mixed connective tissue disease (MCTD) has certain features in common with systemic lupus erythematosus (SLE), systemic sclerosis (SS), rheumatoid arthritis (RA) and polymyositis (PM) (1). The diagnosis of MCTD requires the presence of features of at least two systemic connective tissue diseases, high serum titres of antiribonucleoprotein antibodies (anti-RNP), and three or more of the following: arthritis, myositis, Raynaud's phenomenon, sclerodactyly and swelling of the hands (2, 3). The renal disease in MCTD usually appears as mild glomerulonephritis (4). We describe three patients with MCTD who developed amyloidosis. One of these patients has previously been described in a case report (5).
