Clinical Utility of Non lnvasive Methods in the Evaluation of Scleroderma Lung in Pediatric Age

F. Falcini Department of Pediatrics, University of Florence, Italy

A. Pignone Institute of Clinical Medicine IV, University of Florence, Italy, Department of Clinical Physiopathology, Respiratory Physiopathology Unit, University of Florence, Italy

M. Matucci-cerinic Institute of Clinical Medicine IV, University of Florence, Italy, Department of Clinical Physiopathology, Respiratory Physiopathology Unit, University of Florence, Italy

G. Camiciottoli Institute of Clinical Medicine IV, University of Florence, Italy, Department of Clinical Physiopathology, Respiratory Physiopathology Unit, University of Florence, Italy

G. Taccetti Department of Pediatrics, University of Florence, Italy

S. Trapani Department of Pediatrics, University of Florence, Italy

E. Zammarchi Department of Pediatrics, University of Florence, Italy

A. Lombardi Institute of Clinical Medicine IV, University of Florence, Italy, Department of Clinical Physiopathology, Respiratory Physiopathology Unit, University of Florence, Italy

G. Bartolozzi Department of Pediatrics, University of Florence, Italy

M. Cagnoni Institute of Clinical Medicine IV, University of Florence, Italy, Department of Clinical Physiopathology, Respiratory Physiopathology Unit, University of Florence, Italy

show all

Abstract

Falcini F, Pignone A, Matucci-Cerinic M, Camiciottoli G, Taccetti G, Trapani S, Zammarchi E, Lombardi A, Bartolozzi G, Cagnoni M. Clinical Utility of Non Invasive Methods in The Evaluation of Scleroderma Lund in Pediatric Age. Scand J Rheumatol 1992: 21: 82–4.

Lung involvement in children affected with Systemic Sclerosis (SSc) has been studied. We used ventilation and perfusion scans and compared the results to those obtained with traditional pulmonary function tests. The vascular pulmonary area was examined with a gama-camera after infusion of ^99mTc micro spheres, while the alveolo-capillary membrane and the airways were investigated after administration of a radioaerosol, (^99mTc DTPA). Pulmonary function tests revealed either alteration of the airways or a considerable involvement of the alveolo-capillary membrane in two patients. On the other hand ventilation scan showed airways alterations and a severe decrease of the alveolo -capillary permeability in all patients.

Our study indicates that ventilation scans may be useful in the diagnosis of early modifications of the lung function also in paediatric age and may complement the data obtained from traditional function tests.

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Clinical Utility of Non lnvasive Methods in the Evaluation of Scleroderma Lung in Pediatric Age

Information for

Open access

Opportunities

Help and information

Clinical Utility of Non lnvasive Methods in the Evaluation of Scleroderma Lung in Pediatric Age

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature