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Original Article

Evaluation of Criteria Contributions for the Classification of Systemic Lupus Erythematosus

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Pages 58-62 | Received 20 May 1992, Accepted 03 Nov 1992, Published online: 12 Jul 2009
 

Abstract

Somogyi L, Čikeš N, Marušić M. Evaluation of Criteria Countributions for the Classification of Systemic Lupus Erythematosus. Scand J Rhcumatol. 1993; 22: 58–62.

The American Rheumatism Association (ACR) preliminary and revised criteria for classification of systemic lupus erythematosus (SLE) were evaluated for sensitivity and specificity in a population of 100 patients with SLE and 100 patients with other rheumatic diseases. Bayes theorem was applied for evaluation of ARA criteria for the classification of SLE and a scoring system was developed which allows simple determination of the probability of SLE. The evaluation revealed considerable differences in values of the ARA criteria. The serologic tests and discoid lupus appeared to be the most distinetive criteria, while Raynaud's phenomenon, oral and nasal ulcers and arthritis were of little value. Comparison of SLE and control patients presenting the same number of criteria revealed that patients with SLE exhibit more distinetive criteria. This finding emphasizes the need for a quantitative evaluation of classification criteria.

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