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Hemoglobin
international journal for hemoglobin research
Volume 1, 1977 - Issue 3
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Original Article

The Cyanogen Bromide and MAI EYL Peptides of the α and β Chains of Human Hemoglobin

W. F. Moo-Penn Hematology Division, Center for Disease Control, Public Health Service, U. S. Department of Health, Education, and Welfare, Atlanta, Georgia, 30333
,
M. H. Johnson Hematology Division, Center for Disease Control, Public Health Service, U. S. Department of Health, Education, and Welfare, Atlanta, Georgia, 30333
,
D. L. Jue Hematology Division, Center for Disease Control, Public Health Service, U. S. Department of Health, Education, and Welfare, Atlanta, Georgia, 30333
&
K. C. Bechtel Hematology Division, Center for Disease Control, Public Health Service, U. S. Department of Health, Education, and Welfare, Atlanta, Georgia, 30333
Pages 233-244 | Published online: 07 Jul 2009
 
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Abstract

Procedures are described for the preparation of cyanogen bromide and maleyl peptides of the α and β chains of human Hemoglobin. These relatively large peptides have facilitated application of automated sequencing techniques to determine mutations fn the primary structure of abnormal hemoglobins.

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