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Hemoglobin
international journal for hemoglobin research
Volume 3, 1979 - Issue 2-3
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Original Article

Hemoglobin Lepore Washington and Hemochromatosis in a Hungarian Patient

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Pages 193-204 | Received 05 Oct 1978, Accepted 03 May 1979, Published online: 07 Jul 2009
 

Abstract

A Hungarian family with four heterozygotes for Hb Lepore Washington is described. One, a 43-year-old male, had high levels of serum iron, saturated iron-binding capacity, and ferritin, and normal levels of folic acid and vitamin B12. Liver biopsy showed slight cirrhosis and marked iron deposition in parenchymal cells and in cells of the reticuloendothelial system. Heavy iron deposition was also found in the bone marrow. The patient is not an alcoholic and has no disease that requires blood transfusion. The hemochromatosis thus seems to be of idiopathic nature.

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