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Hemoglobin
international journal for hemoglobin research
Volume 4, 1980 - Issue 3-4
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Original Article

Unstable Hemoglobins in Japan

Y. Ohba Department of Clinical Pathology, Yamaguchi University School of Medicine 1144 Kogushi, Ube, 755, Japan
,
T. Miyaji Department of Clinical Pathology, Yamaguchi University School of Medicine 1144 Kogushi, Ube, 755, Japan
,
Y. Hattori Department of Clinical Pathology, Yamaguchi University School of Medicine 1144 Kogushi, Ube, 755, Japan
,
K. Fuyuno Department of Clinical Pathology, Yamaguchi University School of Medicine 1144 Kogushi, Ube, 755, Japan
&
M. Matsuoka Department of Clinical Pathology, Yamaguchi University School of Medicine 1144 Kogushi, Ube, 755, Japan
Pages 307-312 | Published online: 07 Jul 2009
 
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Abstract

Ten unstable hemoglobins have been identified in 14 Japanese families (Table I). Five of them which have never been found in other countries are Hb Hirosaki, Hb Iwata, Hb Tochigi, Hb Mizuho, and Hb Toyoake. Hb Köln has been found in four independent families. Eight cases (57% of the total number of families) appear to have occurred by de novo mutation. We will briefly describe two new unstable hemoglobins, Hb Toyoake and Hb Iwata.

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