Hemoglobin Types in Braziliak Populations

Abstract

Population surveys performed in different Brazilian ethnic groups, and comprising 23,606 subjects, disclosed, besides the common S and D types, hemoglobins G and Po: to Alegre, as well as high F, A'₂ and an apparently unstable A₂ variant. Additional studies on isolated families revealed the occurrence of hemoglobins I, Nite rói, D Punjab, M Boston and J Roviqo. Screening for sickle cells was also performed on 17,412 individuals Detailed clinical studies on series of sickle cell anemics were also performed. Due to their special interest, the physico-chemical properties of Hb Porto Alegre are reviewed in some detail.