Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 6, 1982 - Issue 2
3
Views
3
CrossRef citations to date
0
Altmetric
Original Article

Influence of two α-Globin Gene Deletions on Homozygous β°-Thalassemia

, &
Pages 115-129 | Received 31 Jul 1981, Accepted 26 Feb 1982, Published online: 07 Jul 2009
 

Abstract

The favorable influence of α-thalassemia due to a deletion of two α-globin genes (a-thal-1) on homozygous 3°-thalassemia in an adult Chinese woman is described. Her clinical and hematologic condition was milder than usually seen in homozygous β°-thalassemia. With the help of repeated blood transfusions immediately before delivery she gave birth to a physically healthy baby who had the α-thal-1 trait due to two α-globin gene deletions. with Hb Bart's in the cord blood.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.